Head to head: Comparing intracranial volumes using 3D ultrasound and fetal MRI

Inge M van Ooijen; Gaby van Iersel; Lotte Meijerink; Jalmar Teeuw; Elise Turk; Maaike Nijman; Daniel Cromb; Alena Uus; Serena J. Counsell; Mireille N. Bekker; Maria Luisa Tataranno; Hilleke E. Hulshoff Pol; Sonja M. C. de Zwarte; Manon J N L Benders

doi:10.1016/j.neuroimage.2025.121633

December 1, 2025NeuroImageOpen Access

Head to head: Comparing intracranial volumes using 3D ultrasound and fetal MRI

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Key Points

3D ultrasound yields comparable ICV measurements to fetal MRI around 30 weeks of gestation.
The validation of volumetric methods enhances assessment of at-risk fetuses.
Observational analysis supports use of 3D ultrasound where fetal MRI access is limited.
Improved normative curves may enable enhanced fetal development evaluations.

Implication

Analysis shows 3D ultrasound provides comparable ICV measurements to fetal MRI, indicating support for fetal development monitoring.

Abstract

Fetal US and MRI yield comparable ICV measurements around 30 weeks of gestation, validating automatic 3D US volumetric methods. The use of 3D US may support development of normative curves and improve comparisons with at-risk fetuses, including in regions where fetal MRI is less accessible.

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Cite This Study

Ooijen et al. (2025) studied this question.

synapsesocial.com/papers/69402a6b2d562116f2901c17 https://doi.org/10.1016/j.neuroimage.2025.121633

View Full Paper

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Head to head: Comparing intracranial volumes using 3D ultrasound and fetal MRI

Key Points

Implication

Abstract

Discussion

Cite This Study

Head to head: Comparing intracranial volumes using 3D ultrasound and fetal MRI

Key Points

Implication

Abstract

Discussion

Cite This Study

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