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December 1, 2025Acta Medica BulgaricaOpen Access

Endoscopic Endonasal Resection of Advanced Stage T3/T4 Sinonasal Malignancies Involving Skull Base: Monocentric Single-Surgeon Study (2020-2024)

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Authors

TPT. PopovMedical University of SofiaSDS DimitrovMedical University of SofiaVDV. DobriyanovaMedical University of Sofia

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Implication

Retrospective analysis shows 81.3% recurrence-free survival in patients with T3/T4 sinonasal malignancies, highlighting the need for multidisciplinary collaboration.

Key Points

  • Endoscopic endonasal resection achieved a favorable recurrence-free survival rate of 81.3% after 30 months.
  • The cohort involved 16 patients with predominant squamous cell carcinoma and notable complexities in surgical techniques.
  • Retrospective analysis of advanced sinonasal malignancies was performed over the 2020-2024 period.
  • Surgical outcomes suggest that individualized treatment strategies are critical in managing advanced malignancies.

Cite This Study

Popov et al. (2025) studied this question.

synapsesocial.com/papers/69402a7e2d562116f29020cbhttps://doi.org/10.2478/amb-2025-0071
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anatomical Features and Morphometric Characteristics of the Sphenoidal Sinus in MRI Studies2024
  2. 2Endoscopic Resection of Sinonasal Malignancy2016 · 87 citations
  3. 3The MUSES∗: a prognostic study on 1360 patients with sinonasal cancer undergoing endoscopic surgery-based treatment2022 · 55 citations