December 1, 2025International Journal for Numerical Methods in Biomedical EngineeringOpen Access

A Comparison of Coupling Strategies for 1D–3D Simulations of Coronary Hemodynamics

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Authors

PHPjotr HilhorstEindhoven University of Technology AVAmy J.E. VermeerRadboud University Nijmegen KZKarol ZającBydgoszcz University of Science and Technology

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Implication

Analysis reveals steady-state simulations efficiently predict fractional flow reserve in coronary lesions, suggesting benefits of high-fidelity modeling.

Key Points

Steady-state simulations significantly reduce computational costs while predicting fractional flow reserve accurately.
Key findings indicate effective resolution of coronary hemodynamics in complex stenosis geometries through high-fidelity simulations.
Major coupling strategies tested included mean flow-driven steady-state and continuous data exchange transient simulations.
High-fidelity simulations underscore the importance of accurate boundary conditions in modeling coronary physiology.

Cite This Study

Hilhorst et al. (2025) studied this question.

synapsesocial.com/papers/69402a7e2d562116f2902308 https://doi.org/10.1002/cnm.70126

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December 1, 2025International Journal for Numerical Methods in Biomedical EngineeringOpen Access

A Comparison of Coupling Strategies for 1D–3D Simulations of Coronary Hemodynamics

View Full Paper

Ask AI

Bookmark

Authors

PHPjotr HilhorstEindhoven University of Technology AVAmy J.E. VermeerRadboud University Nijmegen KZKarol ZającBydgoszcz University of Science and Technology

Discussion

Member takes

Implication

Analysis reveals steady-state simulations efficiently predict fractional flow reserve in coronary lesions, suggesting benefits of high-fidelity modeling.

Key Points

Steady-state simulations significantly reduce computational costs while predicting fractional flow reserve accurately.
Key findings indicate effective resolution of coronary hemodynamics in complex stenosis geometries through high-fidelity simulations.
Major coupling strategies tested included mean flow-driven steady-state and continuous data exchange transient simulations.
High-fidelity simulations underscore the importance of accurate boundary conditions in modeling coronary physiology.

Cite This Study

Hilhorst et al. (2025) studied this question.

synapsesocial.com/papers/69402a7e2d562116f2902308 https://doi.org/10.1002/cnm.70126

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