Case report reveals rapid metastasis in HER2-positive mammary Paget's disease patients, suggesting urgent follow-up care and monitoring.
Mammary Paget's disease (MPD) with ductal carcinoma in situ (DCIS) pathology can metastasize rapidly. HER2‐positive status likely drives aggression, warranting early postoperative systemic imaging and close surveillance. Anti‐HER2 agents require proactive toxicity management. Personalized dose adjustments and multidisciplinary management are essential to optimize outcomes.
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Wang et al. (2025) studied this question.
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