December 1, 2025MicrobiologyOpenOpen Access

Various Bacillus and Paenibacillus Spp. Isolated From Soil Produce Compounds With Potent Antimicrobial Activity Against Clinically Relevant Pathogens

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Potent antimicrobial activity was observed against clinically relevant pathogens, including CRE and MRSA.
Paenibacillus strains exhibited significant suppression in antimicrobial assays, highlighting their potential.
Investigation utilised genomic methods like 16S rRNA sequencing and antiSMASH analysis to identify biosynthetic pathways.
Findings support the potential of soil-derived Bacillus and Paenibacillus species in developing novel antimicrobial agents.

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Investigation reveals antimicrobial activity against multi-drug resistant pathogens and identifies key compounds like colistin and polymyxin B.

Moran et al. (2025) studied this question.

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Investigation reveals antimicrobial activity against multi-drug resistant pathogens and identifies key compounds like colistin and polymyxin B.