Vibration-Controlled Transient Elastography in Chronic Liver Disease: Current Research Insights

Chronic liver disease (CLD) affects millions worldwide, and non-invasive fibrosis assessment is essential for prognosis and care. Vibration-controlled transient elastography (VCTE) reliably stages fibrosis, predicts treatment response, and identifies high-risk patients with viral hepatitis and metabolic dysfunction-associated steatotic liver disease. VCTE-based scores improve diagnostic accuracy, reduce liver biopsy need, and predict hepatocellular carcinoma and liver-related events. Current practice guidelines recommend incorporating VCTE into treatment and surveillance, underscoring its role in routine practice and value for guiding clinical decisions and improving outcomes in CLD. In this article, we summarized practical aspects of VCTE, reviewed recent evidence regarding its role in the assessment of liver fibrosis and clinical outcomes, and explored its current position in clinical guidelines for CLD.