Premature greying of hair in children: A comprehensive review for pediatricians and primary care physicians

Premature greying of hair (canities) in children is an increasingly recognized concern among parents and pediatricians. Although often benign, early hair depigmentation may be a clinical marker of nutritional deficiencies, autoimmune disorders, genetic predisposition, endocrine abnormalities, or oxidative stress related damage. The absence of standardized pediatrics guidelines leads to misdiagnosis, unnecessary anxiety, and missed opportunities for early intervention. This review synthesizes current evidence on epidemiology, pathophysiology, risk factors, diagnostic approach, and management of premature greying in children. A structured evaluation and targeted treatment of reversible causes especially vitamin B12, iron, vitamin D, zinc deficiency, and hypothyroidism can halt or partially reverse greying in many children. This article provides an evidence-based, clinically practical approach suitable for pediatricians, dermatologists, and general practitioners.