Compromised concept: Link between endometriosis, pregnancy complications and infertility

Endometriosis is a persistent inflammatory condition characterised by chronic pain, increasing the chances of infertility and adverse pregnancy outcomes. However, the existing evidence on this matter lacks consistency. The disease is associated with impaired folliculogenesis exerting a negative effect on egg quality and leading to defects during the luteal phase, decreased rates of fertilisation and abnormal embryonic development, all of which contribute to reproductive difficulties. As the number of endometriosis patients who become pregnant increases, there is a greater demand for comprehensive assessments to identify the possible negative impact of the condition on pregnancy outcomes, including the postnatal period. Patients with endometriosis might experience obstetric complications, including placenta accreta spectrum, fetal growth restriction and a higher likelihood of having to undergo a caesarean section, giving birth prematurely, and experiencing postpartum haemorrhage. The field of obstetrics often neglects to fully recognise and examine these complex issues, leading to the lack of thorough investigation. The impact of the disease extends beyond the conception stage, potentially influencing results in obstetrics and neonatology. Hence, it is imperative to carry out a targeted investigation to determine the most efficient strategies for managing and monitoring pregnant women who were diagnosed with endometriosis. An updated summary of the most recent research in this area is given in this review. An updated summary of the most recent research in this area is given in this review.