Comparison of Visual Evoked Potential in Patients with Attention-deficit/Hyperactivity Disorder in Medication and Non-medication Group

Aim: Attention-deficit/hyperactivity disorder (AD/HD) is a common neuropsychiatric disorder resulting from disruptions in circuits that regulate attention and action. Many studies have revealed different parameters of AD/HD through neurophysiological measurements. The purpose of this study is to compare visual evoked potentials (VEPs) latency and amplitude in AD/HD patients. This study aims to discuss the effects of disease severity and psychostimulants use on the central nervous system based on VEP measurements. Methods: The study was designed using a retrospective-descriptive methodology, including a total of 30 patients diagnosed with AD/HD, 15 of whom were taking psychostimulant medication and 15 of whom were not, who presented to the psychiatry outpatient clinic between January 2024 and June 2024. P-100 amplitude and latency were recorded for both eyes. In AD/HD patients, these values were compared based on the severity of the disease, between those who receive treatment and those who do not. Results: There was no statistically significant difference between latency and amplitude values according to disease severity. The difference was statistically significant between P-100 latency according to psychostimulant use (p=0.046, p=0.016). With regard to the use of psychostimulants, there was no significant difference in the amplitude values. Conclusion: VEP studies with increased sample size AD/HD, with additional confounding variables, will provide insight into information processing and shed light on the pathophysiology of AD/HD.