Clinical study on whitening effects and tooth sensitivity of home-whitening agents containing 6% hydrogen peroxide

This study aimed to compare the efficacy of tooth whitening and prevalence of tooth sensitivity between 6% hydrogen peroxide (HP) and 10 % carbamide peroxide (CP) at-home whitening systems. Forty-eight patients were chosen and divided into two groups: 6% HP (Tion Take Home With, WI) and 10% CP (Tion Take Home Platinum, PL). Both groups followed the manufacturer's instructions. The whitening procedures were performed over a 10 day period of 1 h per day in WI and a 14 day period of 2 h per day in PL. Tooth color changes were measured with a spectrophotometer. The pain intensity was assessed using a numerical rating scale. No significant differences in ΔE*ab, ΔE₀₀, and ΔWID were found between the groups. Tooth sensitivity was more prevalent in WI than in PL. Ten days of 6% HP use was as effective as 14 days of 10% CP.