Lesion morphology from intracoronary pullback independently influences treatment in stable CAD, alongside severity and symptoms. PCI is typically chosen for focal lesions, whereas diffuse disease often results in deferring revascularization, even with significant ischemia (FFR ≤0.75). This shows that lesion morphology can take precedence over functional severity when deciding treatment.
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Slegers et al. (2025) studied this question.
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