Objectives: This study aims to present an AI-driven threat-hunting framework that automates both hypothesis generation and hypothesis validation through a hybrid deep learning model that combines Convolutional Neural Networks (CNN) with Long Short-Term Memory (LSTM) networks. The objective is to operationalize proactive threat hunting by embedding anomaly detection within a structured workflow, improving detection performance, reducing analyst workload, and strengthening overall security posture. Methods: The framework begins with automated hypothesis generation, in which the model analyzes network flows, telemetry data, and logs sourced from IoT/IIoT devices, Windows/Linux systems, and interconnected environments represented in the TON_IoT dataset. Deviations from baseline behavior are detected as potential threat indicators, and hypotheses are prioritized according to anomaly confidence scores derived from output probabilities. Validation is conducted through iterative classification, where CNN-extracted spatial features and LSTM-captured temporal features are jointly used to confirm or refute hypotheses, minimizing manual data pivoting and contextual enrichment. Principal Component Analysis (PCA) and Recursive Feature Elimination with Random Forest (RFE-RF) are employed to extract and rank features based on predictive importance. Results: The hybrid model, trained on the TON_IoT dataset, achieved strong performance metrics: 99.60% accuracy, 99.71% precision, 99.32% recall, an AUC of 99%, and a 99.58% F1-score. These results outperform baseline models such as Random Forest and Autoencoder. By integrating spatial and temporal feature extraction, the model effectively identifies anomalies with minimal false positives and false negatives, while the automation of the hypothesis lifecycle significantly reduces analyst workload. Conclusions: Automating threat-hunting processes through hybrid deep learning shifts organizations from reactive to proactive defense. The proposed framework improves threat visibility, accelerates response times, and enhances overall security posture. The findings offer valuable insights for researchers, practitioners, and policymakers seeking to advance AI adoption in threat intelligence and enterprise security.
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Kamande et al. (2025) studied this question.
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