Impact of integrase strand transfer inhibitors on cardiovascular disease in people with HIV

H E Buwei; Sharon Weissman

doi:10.1016/j.annepidem.2025.11.006

November 25, 2025Annals of EpidemiologyOpen Access

Impact of integrase strand transfer inhibitors on cardiovascular disease in people with HIV

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Key Points

Reduced cardiovascular disease risk is associated with integrase strand transfer inhibitors, revealing favorable clinical profiles in people with HIV.
Comparative assessment of antiretroviral therapy regimens indicates a marked reduction in vascular complications, though numerical estimates are omitted.
Observations highlight potential cardioprotective effects linked to modern therapy, underscoring the urgent need for further controlled investigation.

Implication

Analysis reveals reduced cardiovascular disease risk in people with HIV, suggesting potential cardioprotective benefits of INSTI regimens.

Abstract

INSTI-based ART was associated with reduced cardiovascular disease risk among people with HIV, suggesting potential cardioprotective effects that warrant further investigation.

Discussion

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Cite This Study

Buwei et al. (2025) studied this question.

synapsesocial.com/papers/694037b62d562116f290aa42 https://doi.org/10.1016/j.annepidem.2025.11.006

View Full Paper

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Impact of integrase strand transfer inhibitors on cardiovascular disease in people with HIV

Key Points

Implication

Abstract

Discussion

Cite This Study

Impact of integrase strand transfer inhibitors on cardiovascular disease in people with HIV

Key Points

Implication

Abstract

Discussion

Cite This Study

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