Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
November 25, 2025Biochemistry

Distal Mutations Rewire Allosteric Networks to Control Substrate Specificity in PTP1B

View Full Paper
Ask AI
Bookmark
Share

Authors

XWXiaoyuan WangRARyan M. AndersonJLJinchan LIU

Discussion

Loading...

Member takes

Overview

Key Points

Key points are not available for this paper at this time.

Cite This Study

Wang et al. (2025) studied this question.

synapsesocial.com/papers/694039a72d562116f290bb20https://doi.org/10.1021/acs.biochem.5c00539
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Distal Mutations Rewire Allosteric Networks to Control Substrate Specificity in PTP1B2025 · 4 citations
  2. 2Native dynamics and allosteric responses in <scp>PTP1B</scp> probed by high‐resolution <scp>HDX‐MS</scp>2024 · 26 citations
  3. 3Distinct Conformational Switches Control WPD‐Loop Dynamics Across Protein Tyrosine Phosphatase Subfamilies2026
  4. 4BPS2026 – Allosteric inhibition mechanism of PTP1B using molecular dynamics simulation2026
  5. 5Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy2024 · 8 citations