Dietary n‐3 Polyunsaturated Fatty Acids From Fish Are Associated With Better Healthy Aging Indicators: Results of the DIAPELH Study

Introduction Promoting healthy aging is a public health goal, especially in regions with a high proportion of older adults, such as Greece. This cross‐sectional study investigated the association of fish n‐3 PUFA intake with indicators of healthy aging among older Greek Peloponnesian adults. Methods In total, 449 individuals > 60 years of age were enroled. Sociodemographic, anthropometrical, medical, mobility, balance, lifestyle, dietary, cognitive and mental characteristics were assessed through validated questionnaires and procedures. Results Analyses revealed that n‐3 PUFA intake was associated with fewer depression symptoms ( p < 0.001), higher cognition levels ( p = 0.012) and levels of healthy aging ( p < 0.001), derived from Successful Aging Index (SAI). In parallel, n‐3 PUFA intake was associated with higher adherence to the Mediterranean diet ( p < 0.001). Additionally, n‐3 PUFA intake was inversely correlated with the presence of long COVID‐19 symptomatology ( p = 0.036). No association of n‐3 PUFA intake with mobility or physical performance and balance (all p s> 0.05) was detected. Conclusion The results underscore the significance of nutrition in older adults, highlighting the possible protective impact of n‐3 PUFAs on maintaining functionality. Future prospective studies may validate these associations and contribute to the development of targeted nutritional strategies for older adults.