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November 24, 2025World Journal of Surgical OncologyOpen Access

Consensus Molecular Subtypes (CMS) Classification: a progress towards Subtype-Driven treatments in colorectal cancer

Akshay Kantha Doutrina Das Esha Pai Tarun Kumar Manoj Pandey

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Abstract

CMS classification enhances CRC prognosis and treatment personalization but faces challenges due to ITH and technical limitations. Advances in IHC, imCMS, and targeted gene panels may facilitate broader clinical adoption, improving patient outcomes through tailored therapies.

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Cite This Study

Kantha et al. (2025) studied this question.

synapsesocial.com/papers/69403bab2d562116f290ce74 https://doi.org/10.1186/s12957-025-04117-1

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5Abstract 5059: Robust single sample consensus molecular subtype classification for primary and metastatic colorectal cancer2024