Purpose: To describe the evolution of health-related quality of life (HRQoL) 12 months after eye amputation surgery and to identify the factors influencing HRQoL. Design: A prospective cohort study was conducted. Methods: • Setting: A monocentric study was performed. • Patient Population: A total of 35 patients who had to undergo a surgical eye amputation were included and followed for a period of 12 months. • Intervention: Three standardized HRQoL questionnaires were filled at two time points: 3 months postoperatively (initial phase) and 12 months postoperatively (subsequent phase). The questionnaires were the following: The National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25), the Short Form-36 (SF-36), and the Perceived Stress Scale (PSS). • Main Outcome Measure: The variation in the quality of life as reflected in the NEI VFQ‐25 score compared at 3 months to 12 months after surgery. Results: No significant difference was observed in the multidimensional analysis scales of the HRQoL 12 months after eye amputation surgery. Regarding the VFQ-25 subscales, the peripheral visual field and the dependence on others were significantly improved at 12-month follow-up ( P < 0.01). A multivariate analysis conducted at the 12-month follow-up revealed a significant association between a history of stroke and a decline in physical quality of life. Conclusions: The improvement and stabilization of HRQoL in patients who have undergone ocular amputation surgery are indicative of adaptative mechanisms. It would be beneficial to implement a tailored preparation program for patients with factors that may impact HRQoL prior to undergoing this surgical procedure.
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Sarubbi et al. (2025) studied this question.
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