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November 23, 2025Journal of Orthopaedic Surgery and ResearchOpen Access

LINC00482 targets miR-877-3p to modulate osteogenic differentiation in fracture patients

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Abstract

LINC00482 may inhibit osteoblast proliferation and osteogenic differentiation by targeting miR-877-3p, thereby impeding fracture healing.

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Cite This Study

Wei He (2025) studied this question.

synapsesocial.com/papers/69403fa32d562116f290e3e5 https://doi.org/10.1186/s13018-025-06519-z

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Functional mechanism and clinical implications of LINC00339 in delayed fracture healing2024 · 12 citations
2LINC01271 promotes fracture healing via regulating miR-19a-3p/PIK3CA axisIn Vitro Study · 2025 · 5 citations
3MicroRNA-877-5p promotes osteoblast differentiation by targeting EIF4G2 expression2024 · 15 citations
4LINC00323 induced by hypoxia promote cartilage callus by interacting with FUS to regulate PDGFB expression2024
5miR-34a-5p targets Foxp1 to promote osteoclast differentiation and accelerate fracture healing2025

More related papers

miR-296-3p Controls Osteogenic Proliferation and Differentiation by Targeting ICAT and Is Involved in Fracture Healing2025
miR-211-5p/FOXO3 axis accelerates osteogenic differentiation and fracture healing by mediating Wnt/β-catenin pathway2026
LINC01133 promotes the osteogenic differentiation of bone marrow mesenchymal stem cells by upregulating CTNNB1 by acting as a sponge for miR-214-3p2024

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