⌘+K

Pulse Explore Clubs Researchers Journals

Home Clubs Explore

November 23, 2025Discover OncologyOpen Access

Prediction of prognostic biomarkers for hepatocellular carcinoma and immune microenvironment infiltration based on single-cell sequencing and RNA-Seq integration

Yiyan Zhai Xuan Fan Huangshu Lei Tong Zhao

View Full Paper

Ask AI

Bookmark

Share

Abstract

This study identified and validated prognostic biomarkers in HCC that effectively predict patient survival rates and immune infiltration characteristics. These findings provide a potential foundation for precision medicine strategies in HCC, offering novel insights into the tumor-immune microenvironment and its clinical implications.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Zhai et al. (2025) studied this question.

synapsesocial.com/papers/69403fa32d562116f290e5ea https://doi.org/10.1007/s12672-025-04094-7

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Prediction of prognostic biomarkers for hepatocellular carcinoma and immune microenvironment infiltration based on single-cell sequencing and RNA-Seq integration2025
2Identification of immune cell-related prognostic genes characterized by a distinct microenvironment in hepatocellular carcinoma2024 · 1 citations
3Integrated single-cell and bulk RNA-seq analysis reveals an NK-cell-related immune landscape and a prognostic signature for hepatocellular carcinomaOriginal Research · 2026
4Construction of an immune-related signature based on single-cell RNA-sequencing and machine learning for optimal prognosis prediction and treatment decisions in hepatocellular carcinoma2024
5Prediction of Prognosis in Patients with Hepatocellular Carcinoma Based on Molecular Subtypes of Immune GenesOriginal Research · 2022