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November 23, 2025MedCommOpen Access

Inflammasome Activation Differences Underpin Different Mycobacterium tuberculosis Infection Outcomes

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Authors

RKRanjeet KumarAKAfsal KolloliGBGunapati Bhargavi

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Kumar et al. (2025) studied this question.

synapsesocial.com/papers/69403fa82d562116f290e62chttps://doi.org/10.1002/mco2.70486
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Inflammasome Activation Differences Underpin Different <i>Mycobacterium tuberculosis</i> Infection Outcomes2025
  2. 2<i>Mycobacterium tuberculosis</i> does not inhibit NLRP1 and pyrin inflammasomes in human macrophages2026
  3. 3Genetically diverse Mycobacterium tuberculosis isolates manipulate inflammasome activation and IL-1β secretion independently of macrophage metabolic rewiring2024
  4. 4<i>Mycobacterium tuberculosis</i> Utilizes Serine/Threonine Kinase PknF to Evade NLRP3 Inflammasome-driven Caspase-1 and RIPK3/Caspase-8 Activation in Murine Dendritic Cells2024 · 2 citations
  5. 5Differential activation of NF-Κβ and HIF-1α between fetal liver-derived and myeloid-derived macrophages drives inflammatory differences following <i>Mycobacterium abscessus</i> infection2026