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Analytical techniques find particles in catheter lines after drug co-administration, suggesting better observation methods.
Raman spectroscopy in combination with a database was used for rapid and non-invasive bulk identification in situ. However, to confirm or refute small amounts of a second drug substance in the precipitate, a large area scan of the particle on a flat surface is recommended.
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Hagesæther et al. (2025) studied this question.
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