What type of study is this?

This is a Systematic Review study.

What question did this study set out to answer?

To quantify peri-operative morbidity and mortality risks in patients with aortic stenosis undergoing non-cardiac surgery.

December 12, 2025AnaesthesiaOpen Access

Peri‐operative risk of non‐cardiac surgery in patients with aortic stenosis: a systematic review and meta‐analysis

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Authors

APAmelia PlaceThe Royal Melbourne Hospital TRThalys Sampaio RodriguesThe University of Melbourne PNPhillip S. NaimoThe Royal Melbourne Hospital

Discussion

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Implication

Systematic review demonstrates increased mortality and myocardial infarction risk in aortic stenosis patients undergoing non-cardiac surgery, highlighting peri-operative management needs.

Key Points

To quantify peri-operative morbidity and mortality risks in patients with aortic stenosis undergoing non-cardiac surgery.
Systematic review and meta-analysis of relevant studies
Searched databases for studies examining aortic stenosis in non-cardiac surgery
Primary endpoint: all-cause mortality; secondary endpoints included myocardial infarction, heart failure, stroke, delirium, venous thromboembolism, acute kidney injury.
Included 19 studies with 100,486 patients
Estimated all-cause mortality was 3.8% for all degrees of aortic stenosis
Mortality was 9.6% for severe aortic stenosis
Relative risk of mortality in aortic stenosis patients was 1.58 compared to those without
Increased risk of postoperative myocardial infarction (relative risk 1.79) and heart failure (relative risk 2.06)

Cite This Study

Place et al. (2025) studied this question.

synapsesocial.com/papers/6941aae10f5af7fd17df5a82 https://doi.org/10.1111/anae.70084

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Implication

Systematic review demonstrates increased mortality and myocardial infarction risk in aortic stenosis patients undergoing non-cardiac surgery, highlighting peri-operative management needs.

Peri‐operative risk of non‐cardiac surgery in patients with aortic stenosis: a systematic review and meta‐analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

Peri‐operative risk of non‐cardiac surgery in patients with aortic stenosis: a systematic review and meta‐analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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