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December 10, 2025European Heart Journal - Case Reports1 citationsOpen Access

Case report: the management dilemma of a large left ventricular fibroma

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MGMarília Cristina Cunha GomesDMD. MooreWTW. Taggu

Key Points

  • To discuss the management challenges of a large left ventricular fibroma in an adult patient.
  • Case report of a 40-year-old male with a large left ventricular fibroma.
  • Utilized multimodal imaging techniques: CT coronary angiography, transthoracic echocardiography, cardiac magnetic resonance imaging, PET-CT.
  • Adopted a conservative management strategy including regular holter monitoring and echocardiography.
  • The patient was found to have a 42 x 30 x 58 mm myocardial mass classified as a fibroma via biopsy.
  • Asymptomatic status and high surgical risk led to conservative management instead of resection.
  • Regular monitoring showed no immediate arrhythmias or tumour progression.

Abstract

Abstract Background Cardiac fibromas are rare, benign primary cardiac tumours predominantly observed in paediatric populations, with their occurrence in adults being exceptionally uncommon. Case Summary We present the case of a 40-year-old physically active male with an incidentally discovered, large left ventricular fibroma during investigation for presumed ischaemic heart disease. Multimodal imaging, including CT coronary angiography, transthoracic echocardiography, cardiac magnetic resonance imaging, and PET-CT, revealed a 42 x 30 x 58 mm myocardial mass with significant calcification and myocardial invasion, ultimately diagnosed as a fibroma via biopsy. Given the patient’s asymptomatic status, frequent ventricular ectopics, and high surgical risk associated with resection, a conservative management strategy was adopted. This included regular holter monitoring and echocardiography to assess for arrhythmias, tumour progression, or functional compromise. The case underscores the limited evidence available for managing cardiac fibromas in adults, necessitating extrapolation from paediatric data and an individualised, patient-centred approach. Discussion This report highlights the challenges of decision-making in adult cardiac fibromas, particularly regarding arrhythmogenic potential and surgical considerations, and emphasises the need for further studies to establish evidence-based guidelines for this rare condition.

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Cite This Study

Gomes et al. (2025) studied this question.

synapsesocial.com/papers/6941aaf00f5af7fd17df5c44https://doi.org/10.1093/ehjcr/ytaf644
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