December 1, 2025Alzheimer s & DementiaOpen Access

Unraveling the oral microbiome's role in Alzheimer's disease: From pathophysiology to therapeutic potential

View Full Paper

Ask AI

Bookmark

Authors

Discussion

Observational analysis revealed oral microbiome dysbiosis impacts Alzheimer's disease, suggesting probiotics and prebiotics may mitigate risks.

Oral microbiome dysbiosis drives neuroinflammation in Alzheimer's disease, increasing amyloid beta aggregation.
Key pathogens include Treponema denticola and Fusobacterium nucleatum, promoting virulence factors complicating AD.
Biomarkers in saliva, like Veillonella, could facilitate early Alzheimer's disease detection; implications are significant.
Targeted interventions involving probiotics and prebiotics represent a promising therapeutic potential for Alzheimer's disease.

Rozenblum et al. (2025) studied this question.

View Full Paper

Ask AI

Bookmark

Observational analysis revealed oral microbiome dysbiosis impacts Alzheimer's disease, suggesting probiotics and prebiotics may mitigate risks.