What question did this study set out to answer?

To evaluate the institutional variation and factors associated with fentanyl use in children on ECMO.

December 19, 2025Hospital Pediatrics

Institutional Variation in Fentanyl Use for Children on Extracorporeal Membrane Oxygenation

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To evaluate the institutional variation and factors associated with fentanyl use in children on ECMO.
Retrospective study with children under 18 on ECMO from 2016 to 2023
Utilized the Pediatric Health Information System database
Employed multivariable hierarchical logistic regression analysis for factors associated with fentanyl use
7731 children were included with 91.9% receiving fentanyl during ECMO
Institutional variability in fentanyl use ranged from 13.4% to 100%
Neonates had the highest likelihood of fentanyl use (OR 2.35)
Children with cardiovascular disease were more likely to receive fentanyl (OR 1.63) and those with prematurity were less likely (OR 0.50)

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Implication

Retrospective analysis reveals significant institutional differences in opioid analgesic use for children on ECMO, highlighting risks associated with prematurity and cardiovascular conditions.

Cite This Study

Barq et al. (2025) studied this question.

synapsesocial.com/papers/69449a922f0218eca95087f3 https://doi.org/10.1542/hpeds.2025-008661

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Implication

Retrospective analysis reveals significant institutional differences in opioid analgesic use for children on ECMO, highlighting risks associated with prematurity and cardiovascular conditions.

Institutional Variation in Fentanyl Use for Children on Extracorporeal Membrane Oxygenation

Key Points

Discussion

Implication

Cite This Study

Institutional Variation in Fentanyl Use for Children on Extracorporeal Membrane Oxygenation

Key Points

Discussion

Implication

Cite This Study

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