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December 20, 2025Indian Journal of Medical and Paediatric Oncology0 citationsOpen Access

Clinicopathological Characteristics and Survival Outcomes of Metaplastic Breast Cancer

Clinicopathological Characteristics and Outcomes of Metaplastic Breast Cancer: Experience from a Tertiary Cancer Center in India

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Authors

VVVijaya Lakshmi Vemula VenkataDTDonna C. P. TharappelGVGanesha Dev Vashishta

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Overview

Retrospective analysis reveals that neoadjuvant chemotherapy limits survival outcomes in patients with metaplastic breast cancer, suggesting the need for tailored treatment strategies.

Key Points

  • The study evaluates the clinicopathological features, treatment responses, and survival outcomes of patients with metaplastic breast cancer (MBC).
  • Retrospective analysis of 20 patients diagnosed with MBC from 2012 to 2025
  • Assessment of clinicopathological characteristics, treatment modalities, and survival outcomes
  • Evaluation of neoadjuvant chemotherapy and its impact on overall survival
  • Median age at presentation was 59.5 years
  • 75% of patients had triple-negative receptor status
  • Overall survival rates at 1, 3, and 5 years were 84.4%, 65.1%, and 48.8%, respectively.
  • Tumor recurrence occurred in 25% of patients
  • Statistically significant worsening of overall survival associated with neoadjuvant chemotherapy (HR: 6.13, p = 0.040)

Cite This Study

Venkata et al. (2025) studied this question.

synapsesocial.com/papers/6945e9325151ab1219e4d513https://doi.org/10.1055/s-0045-1814394
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