Nationally representative analysis finds higher mortality and costs in children with complex chronic conditions, suggesting a need for cost-effectiveness improvements.
BACKGROUND Children with medical complexity (CMC) are an evolving patient population at high risk of adverse health care outcomes while hospitalized. OBJECTIVE Using a nationally representative cohort, we aimed to compare hospitalization resource use for CMC to non-CMC. METHODS Using the 2022 Kids’ Inpatient Database, we identified CMC by the presence of at least 1 complex chronic condition (CCCs) and grouped CMC by 1, 2, or 3 or more CCC. The outcomes were length of stay, hospitalization costs, and in-hospital mortality across CMC groupings compared with non-CMC. RESULTS Of 3 169 944 pediatric hospitalizations in the United States, 389 127 (12.3%), 118 257 (3.7%), and 155 196 (4.9%) had 1 CCC, 2 CCC, and 3 or more CCC, respectively. Relative to non-CMC, each CMC group had significantly higher odds of in-hospital mortality (1 CCC: adjusted odds ratio [aOR] 31.3 [29.0, 33.7], P < .001; 2 CCC: aOR 53.5 [49.1, 58.2], P < .001; 3+ CCC: aOR 66.9 [61.1, 73.4], P < .001), longer length of stay in days (1 CCC: >3.20, [2.95, 3.44], P < .001; 2 CCC: >6.50, [5.97, 7.02], P < .001; 3+ CCC: >11.6 [10.8, 12.4], P < .001), and higher hospitalization costs (1 CCC: >$13 388 [11 947, 14 829], P < .001; 2 CCC: >$29 426 [26 233, 32 619], P < .001; 3+ CCC: >$57 426 [51 272, 63 580], P < .001). CONCLUSIONS We highlight substantial health services use and in-hospital mortality for CMC compared with non-CMC. Health systems can use our findings to analyze cost-effectiveness of targeted interventions for CMC, as well as advocate for policy-based changes to reduce hospital- and individual-level inequities for CMC.
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Gabbay et al. (2025) studied this question.
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