What question did this study set out to answer?

To investigate the hepatoprotective effect of Fucus vesiculosus L. on high-fat diet induced obesity in mice.

December 24, 2025International Journal of Biosciences (IJB)

Fucus vesiculosus L. (Bladderwrack) modulates oxidative stress and inflammation on high-fat diet induced obesity in mice

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Implication

Experimental study shows hepatoprotective effect of Fucus vesiculosus against obesity-related liver injury in C57BL/6J mice, indicating beneficial roles in inflammation and oxidative stress.

Key Points

To investigate the hepatoprotective effect of Fucus vesiculosus L. on high-fat diet induced obesity in mice.
Forty male C57BL/6J mice were divided into four groups: control, HFD, Fv, and HFD + Fv.
Fucus vesiculosus was administered at 575 mg/kg body weight/day for 6 weeks orally.
Body weight, liver enzymes, lipid profile, oxidative stress markers, inflammatory cytokines, and liver histopathology were evaluated.
Fucus vesiculosus improved biochemical parameters and alleviated liver steatosis.
Body weight gain was regulated in HFD mice supplemented with Fv.
It downregulated the expression of SREBP-1c, fatty acid synthase, TNF-α, and IL-6 genes.

Cite This Study

A 2019 study studied this question.

synapsesocial.com/papers/694b2d99fc766d0f5c0ed7be https://doi.org/10.12692/ijb/14.6.184-196

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Implication

Experimental study shows hepatoprotective effect of Fucus vesiculosus against obesity-related liver injury in C57BL/6J mice, indicating beneficial roles in inflammation and oxidative stress.

Fucus vesiculosus L. (Bladderwrack) modulates oxidative stress and inflammation on high-fat diet induced obesity in mice

Discussion

Member takes

Implication

Key Points

Cite This Study

Fucus vesiculosus L. (Bladderwrack) modulates oxidative stress and inflammation on high-fat diet induced obesity in mice

Discussion

Member takes

Implication

Key Points

Cite This Study

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