Background: Automatic detection of abnormal electroencephalogram (EEG) signals is essential for supporting clinical screening and reducing human error in EEG interpretation. Although deep learning architectures such as CNN–LSTM have shown promising performance in EEG classification, challenges related to feature variability, non-stationarity, and sensitivity to pathological patterns remain. Our previous work with windowing-based CNN-LSTM architecture achieved strong performance but it did not achieve sufficient sensitivity for reliable clinical application. Methods: To overcome these limitations, we propose an enhanced voting-based ensemble framework that combines five CNN-LSTM base classifiers with a Random Forest (RF) meta-classifier, evaluated using 10-fold cross-validation. Results: The proposed ensemble model achieved a sensitivity of 92.86%, a specificity of 72.3%, and an overall accuracy of 83%, demonstrating competitive and clinically meaningful sensitivity for abnormal EEG detection under the adopted evaluation protocol. Conclusions: These findings demonstrate that integrating multi-model feature extraction with an RF-based voting ensemble improves diagnostic reliability, reduces false negatives, and supports early and accurate detection of brain disorders. This framework not only surpasses existing approaches but also provides a flexible foundation for future advancements in clinical decision support systems.
Abooelzahab et al. (Sun,) studied this question.