Background/Aims It is controversial whether insulin resistance and hyperinsulinemia in preeclamptic patients are due to weight gain during pregnancy or preeclampsia. This study aims investigation of the relation between insulin resistance and weight gain, obesity, biochemical parameters and fetal outcomes of insulin resistance in pregnant women with mild and severe preeclampsia without gestational diabetes. Methods This research was performed in Perinatology Department of Tepecik Training and Research Hospital. Non-diabetic preeclamptic 101 pregnant women between 18-44 years of age in 24-40 gestational weeks were involved in the research. Demographic data, biochemical parameters, weight measurements ,enquiries regarding glucose metabolism and data about fetuses were recorded.Homeostatic Model Assessment (HOMA) value of 2.5 and above and insulin sensitivity index below 6 were evaluated as insulin resistance. Results There is no remarkable variation in both groups concerning fasting and postprandial glucose level, HOMA-IR (homeostatic model assessment insulin resistance), insulin sensitivity index. Only, postprandial insulin was significantly higher in severe preeclampsia group (p
Okay et al. (Tue,) studied this question.
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