What question did this study set out to answer?

To illustrate the gastrointestinal injury associated with doxycycline use, particularly in the context of Lyme disease.

January 6, 2026ACG Case Reports Journal0 citationsOpen Access

Doxycycline-Induced Gastrointestinal Injury for Potential Lyme Disease Exposure

SGSapana R. GuptaBrown University RLRyan LiuBrown University LCLindsey ChannenRhode Island Hospital

Key Points

To illustrate the gastrointestinal injury associated with doxycycline use, particularly in the context of Lyme disease.
Case report of gastrointestinal injury due to doxycycline
Evaluation of histological findings due to doxycycline exposure
Review of literature on doxycycline-related injuries
Demonstrated incidence of gastrointestinal bleeding secondary to doxycycline use
Highlighted characteristic histological findings of doxycycline-induced injury
Emphasized the importance of recognizing drug-specific injury patterns

Abstract

ABSTRACT Doxycycline is an antibiotic frequently used to treat tick-borne diseases. It is known to cause esophageal injury, although gastric injury is less often described. Few cases have been reported of gastrointestinal bleeding secondary to biopsy-proven doxycycline use. In the setting of widespread doxycycline use, it is important to recognize this drug-specific pattern of injury to guide appropriate patient management. This case demonstrates doxycycline-induced gastrointestinal injury and highlights characteristic histological findings.

问 AI

Bookmark

View Full Paper