Evaluation of spin in abstracts of systematic reviews and meta-analyses of mesenchymal stem cell injections for treatment of knee osteoarthritis.

Key Points

• To evaluate the prevalence of spin in systematic reviews and meta-analyses of mesenchymal stem cell injections for knee osteoarthritis.
• Evaluated abstracts of systematic reviews and meta-analyses
• Analyzed the prevalence of spin in reporting
• Assessed association between publication year and reporting bias
• High prevalence of spin in identified reviews
• Publication year correlates with biased favorable outcomes
• Outcomes favoring mesenchymal stem cell intervention are overemphasized