Treatment-resistant schizophrenia (TRS) poses significant challenges. Clozapine, the most effective antipsychotic for TRS, is underused due to its side effect profile and intensive monitoring requirements during initiation. This article describes a collaborative virtual ward model in Peterborough, UK, for community-based clozapine initiation. Integrating wearable technology for real-time health tracking with video consultations, the service provides hospital-equivalent care at home. A partnership between Cambridgeshire and Peterborough NHS Foundation Trust and North West Anglia NHS Foundation Trust merges mental health expertise with acute care infrastructure. Early experiences suggest higher patient engagement, increased clinician confidence and reduced inpatient burden. This initiative has the potential to transform clozapine access, bridge physical and mental health services and offer a blueprint for patient-centred TRS care.
Krishnadas et al. (Tue,) studied this question.