Site-specific N-Glycoproteomic analysis of four M2 macrophage subtypes derived from human THP-1 cells

Key Points

• To investigate site-specific N-glycosylation patterns in M2 macrophage subtypes.
• Utilized glycoproteomic approaches for analysis.
• Employed N-glycan structural characterization tool StrucGP.
• Examined four distinct M2 macrophage subtypes derived from THP-1 cells.
• Identified alterations in glycopeptides across M2 macrophage subtypes.
• Characterized specific N-glycosylation patterns unique to each subtype.