Introduction: In this case report, we present the case of a 69-year-old man with type II diabetes who developed gynecomastia after taking sitagliptin as antidiabetic treatment. Case Presentation: A 69-year-old man with type II diabetes mellitus, who had been receiving a com-bination tablet containing sitagliptin 50 mg and metformin 1000 mg twice daily as antidiabetic ther-apy, developed breast enlargement after two months of treatment. No gynecomastia was reported during pretreatment or post-treatment observation. Furthermore, he did not take drugs causing gyne-comastia; he intended to stop this treatment and switch to another one. Conclusion: According to the report, gynecomastia in this patient may be related to the use of sitagliptin. Further studies are important to ensure this effect.
Abdul-Nabi et al. (Fri,) studied this question.