Key result
Diabetes in HCM is linked to impaired myocardial perfusion and increased subendocardial LGE.
Why the study?
Does concomitant diabetes worsen myocardial perfusion and fibrosis in patients with hypertrophic cardiomyopathy?
Does concomitant diabetes worsen myocardial perfusion and fibrosis in patients with hypertrophic cardiomyopathy?
Concomitant diabetes in patients with hypertrophic cardiomyopathy is associated with worse myocardial perfusion and increased fibrosis on cardiac MRI.
Diabetes may worsen perfusion and fibrosis in hypertrophic cardiomyopathy; hypothesis-generating and requires prospective validation before practice change.
In patients with hypertrophic cardiomyopathy, concomitant diabetes was associated with impaired myocardial perfusion and more frequent subendocardial late gadolinium enhancement at cardiac MRI.
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Yu et al. (2026) studied this question. In patients with hypertrophic cardiomyopathy, diabetes was linked to impaired myocardial perfusion and increased subendocardial late gadolinium enhancement.
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