Deprescribing antihypertensive medications in older people: a systematic review and a meta-analysis

Figures

• 

  Fig. 1. Study flow chart. Study flow chart showing all phases of the process from identification to inclusion

• 

  Fig. 2. Risk of bias graph: Authors’ judgments about each risk of bias reported as percentages across all included studies

• 

  Fig. 3. Risk of Bias Summary. Review authors' judgements about each risk of bias item for the included studies. Green is for low risk, yellow for unclear risk and red for high risk of bias

• 

  Fig. 4. Forest Plot all-cause mortality. Forest plot of the odds ratios of all-cause mortality (event) comparing discontinuation (treatment) versus continuation (control). Fixed Effects - MH denotes the Mantel–Haenszel fixed effect odds ratio of the selected studies (green diamond). The I^2 and H^2 measure the level of levels of inconsistency and heterogeneity (full homogeneity: H^2=1; negligible inconsistency: I^2∈[0,40])

• 

  Fig. 5. Forest Plot myocardial infarction. Forest plot of the odds ratios of myocardial infraction (event) comparing discontinuation (treatment) versus continuation (control). Overall represents odds ratio denotes the MH fixed effect odds ratio of the selected studies. The I^2 and H^2 measure the level of levels of inconsistency and heterogeneity (full homogeneity: H^2=1; negligible inconsistency: I^2∈[0,40])

• 

  Fig. 6. Forest plot heart failure. Forest plot of the odds ratios of heart failure (event) comparing discontinuation (treatment) versus continuation (control). Fixed Effects - MH denotes the Mantel–Haenszel fixed effect odds ratio of the selected studies (green diamond). The I^2 and H^2 measure the level of levels of inconsistency and heterogeneity (full homogeneity: H^2=1; negligible inconsistency: I^2∈[0,40])

• 

  Fig. 7. Forest plot stroke. Forest plot of the odds ratios of stroke (event) comparing discontinuation (treatment) versus continuation (control). Fixed Effects - MH denotes the Mantel–Haenszel fixed effect odds ratio of the selected studies (green diamond). The I^2 and H^2 measure the level of levels of inconsistency and heterogeneity (full homogeneity: H^2=1; negligible inconsistency: I^2∈[0,40])