What question did this study set out to answer?

This research aims to assess the prevalence of anxiety and depression among gastroenterology outpatients and identify associated risk factors.

January 10, 2026BMC Gastroenterology0 citationsOpen Access

Prevalence of anxiety, depression and associated risk factors in gastroenterology outpatients: a multicenter cross-sectional study

Q: What does this research mean for the field?

Anxiety and depression are prevalent among gastroenterology outpatients, particularly those with specific gastrointestinal conditions. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

QDQiang DongNational Clinical Research Center for Digestive Diseases SLSongbo LiNational Clinical Research Center for Digestive Diseases XZXiaojing ZhuNational Clinical Research Center for Digestive Diseases

Key Result

Anxiety and depression were prevalent among gastroenterology outpatients, particularly those with specific gastrointestinal conditions.

Key Points

This research aims to assess the prevalence of anxiety and depression among gastroenterology outpatients and identify associated risk factors.
Conducted a multicenter cross-sectional study
Analyzed psychological status in gastroenterology outpatients
Identified specific gastrointestinal conditions associated with mental health issues
Anxiety and depression were common among the studied population
High prevalence linked with conditions like gastroesophageal reflux and liver disease
Poor sleep was noted as a significant risk factor

Structured PICO

Population

931 gastroenterology outpatients aged 18-75 years who had undergone gastroscopy and colonoscopy within one month, from three central hospitals in Shaanxi Province, China. Median age 49, 54.5% female.

Outcome

Prevalence of anxiety (assessed by Hamilton Anxiety Scale > 14) and depression (assessed by Hamilton Depression Scale > 20) and associated risk factorspatient reported

Anxiety and depression are highly prevalent among gastroenterology outpatients, particularly those with specific gastrointestinal conditions and poor sleep, highlighting the need for psychological screening in this population.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Anxiety and depression were prevalent among gastroenterology outpatients. Gastroenterologists should pay close attention to the psychological status of patients, especially those with gastroesophageal reflux, dyspepsia, bile reflux, atrophic gastritis with intestinal metaplasia or intraepithelial neoplasia, biliary tract disease, liver disease, and poor sleep.

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