Comprehensive profiling of lactylation-associated genes in pulmonary hypertension through bulk and single-cell RNA sequencing integration

Key Result

LCP1 was identified as a key diagnostic marker for pulmonary hypertension in the analysis of lactylation-related genes.

Key Points

• This research aims to profile lactylation-associated genes in pulmonary hypertension and identify potential diagnostic markers.
• Integrated bulk and single-cell RNA sequencing to analyze gene expression.
• Focused on lactylation-related genes in patients with pulmonary hypertension.
• Examined immune cell lactylation patterns within the disease context.
• Identified LCP1 as a significant diagnostic marker for pulmonary hypertension.
• Described the lactylation status of immune cells in patients with pulmonary hypertension.