Most mesalazine-associated adverse events occurred shortly after treatment initiation, with factors like sex and concomitant drugs linked to intolerance.
What are the onset timings and risk factors for mesalazine-related adverse events in Japanese patients?
Mesalazine-associated adverse events typically occur early after treatment initiation, and male sex along with specific concomitant IBD medications are risk factors for mesalazine intolerance.
Absolute Event Rate: 0% vs 0%
Most mesalazine-associated AEs occurred shortly after treatment initiation, although some manifested later. Although direct risk quantification could not be performed from individual RORs, the indicated factors associated with mesalazine intolerance-including sex and specific concomitant drugs might be useful as items for monitoring AEs. These findings provide meaningful insights that may contribute to optimizing therapeutic strategies and improving the quality of life of patients with IBD.
IWAYAMA et al. (Thu,) reported a other. Most mesalazine-associated adverse events occurred shortly after treatment initiation, with factors like sex and concomitant drugs linked to intolerance.