What question did this study set out to answer?

To investigate how three-dimensional margin assessment affects local tumor control during lung cryoablation of colorectal metastases.

January 10, 2026Radiology Imaging Cancer0 citationsOpen Access

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Association between Three-dimensional Margin Assessment and Local Tumor Control in Percutaneous Lung Cryoablation of Colorectal Metastases

Q: What does this research mean for the field?

Quantitatively assessed minimum ablation margins are strongly associated with improved local tumor progression-free survival in lung tumor cryoablation. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

FMFrank MohnThe University of Texas MD Anderson Cancer Center KPKoustav PalThe University of Texas MD Anderson Cancer Center COCaleb S. O’ConnorThe University of Texas MD Anderson Cancer Center

Key Result

Quantitatively assessed minimum ablation margins were strongly associated with improved local tumor progression-free survival in lung tumor cryoablation.

Key Points

To investigate how three-dimensional margin assessment affects local tumor control during lung cryoablation of colorectal metastases.
Quantitative assessment of minimum ablation margins during the procedure.
Evaluation of local tumor progression-free survival rates post-ablation.
Strong correlation found between assessed margins and local tumor progression-free survival.
Reinforces the need for intraprocedural margin assessment to improve outcomes.

Structured PICO

Does three-dimensional margin assessment predict local tumor progression-free survival in patients undergoing percutaneous lung cryoablation of colorectal metastases?

Population

Patients undergoing percutaneous lung cryoablation of colorectal metastases

Intervention

Three-dimensional margin assessment (quantitatively assessed minimum ablation margins)

Outcome

Local tumor progression-free survivalsurrogate

Intraprocedural three-dimensional margin assessment is strongly associated with local tumor control in lung tumor ablation.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Quantitatively assessed minimum ablation margins were strongly associated with local tumor progression-free survival, suggesting the importance of intraprocedural margin assessment in lung tumor ablation.

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Association between Three-dimensional Margin Assessment and Local Tumor Control in Percutaneous Lung Cryoablation of Colorectal Metastases

Key Result

Key Points

Structured PICO

Main Result

Abstract

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