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January 10, 2026Heart Rhythm1 citationsOpen Access

Impact of Left Atrial Posterior Wall Isolation using Pulsed-field Ablation in Patients Undergoing Repeat Catheter Ablation for Atrial Fibrillation

PBPatrick BadertscherCICorinne IseneggerTKThomas Küffer

Key Points

  • This research aims to evaluate the effectiveness of pulsed-field ablation for isolating the left atrial posterior wall in patients with recurrent atrial fibrillation.
  • Analyzed patients undergoing repeat catheter ablation

Structured PICO

Does adjunctive left atrial posterior wall isolation using pulsed-field ablation improve arrhythmia-free survival in patients undergoing repeat catheter ablation for atrial fibrillation?

P
Population
Patients undergoing repeat catheter ablation for atrial fibrillation
I
Intervention
Left atrial posterior wall isolation (PWI) using pulsed-field ablation adjunctive to redo pulmonary vein isolation (PVI)
C
Comparator
Redo pulmonary vein isolation (PVI) without adjunctive PWI
O
Outcome
Arrhythmia-free survivalhard clinical

In patients undergoing repeat ablation for atrial fibrillation, adding posterior wall isolation using pulsed-field ablation to redo PVI increases procedure time without improving arrhythmia-free survival.

Limitations

  • Lack of randomization

Abstract

Redo PVI with or without adjunctive PWI is safe and effective, with comparable arrhythmia-free survival. Adjunctive PWI prolongs procedural duration without improving outcomes. Randomized trials are required to clarify its role.

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Cite This Study

Badertscher et al. (2026) studied this question.

synapsesocial.com/papers/696321f391e05aa366cb8466https://doi.org/10.1016/j.hrthm.2025.12.044
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