Key result
Posterior wall isolation for persistent AF yields conflicting safety and efficacy results.
Why the study?
Pulmonary vein isolation alone results in unsatisfactory recurrence rates in persistent atrial fibrillation, while published clinical studies report conflicting results on the safety and efficacy of posterior wall isolation.
Does posterior wall isolation improve outcomes in patients with persistent atrial fibrillation?
Does posterior wall isolation improve outcomes in patients with persistent atrial fibrillation?
Posterior wall isolation remains a controversial target in persistent atrial fibrillation ablation, with conflicting clinical evidence and a need for careful evaluation of emerging technologies.
No takes yet. Share an insight, caveat, or question.
Should not yet alter clinical practice in persistent AF ablation; leaves open questions on optimized technologies and study design.
Clarke et al. (2021) conducted a review in Persistent atrial fibrillation. Posterior wall isolation was evaluated. Posterior wall isolation for persistent atrial fibrillation currently yields conflicting safety and efficacy results, highlighting the need for optimized ablation technologies and careful study design.
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