What question did this study set out to answer?

This research aims to evaluate the impact of bariatric surgery on epicardial adipose tissue and cardiac function in obese individuals without heart disease.

January 10, 2026Obesity Surgery0 citationsOpen Access

Bariatric Surgery Reduces Epicardial Adipose Tissue and is Associated with Improved Cardiac Function

Q: What does this research mean for the field?

Bariatric surgery reduces epicardial adipose tissue and improves left ventricular function in obese individuals without cardiac disease. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

JCJie Fen ChinInstitute of Cardiology YAYaar AgaErasmus MC SKSabrina Abou KamarHeart Failure / Cardiomyopathy

Key Result

Bariatric surgery led to a reduction in epicardial adipose tissue and improved left ventricular function in obese individuals without cardiac disease.

Key Points

This research aims to evaluate the impact of bariatric surgery on epicardial adipose tissue and cardiac function in obese individuals without heart disease.
Evaluated changes in epicardial adipose tissue after bariatric surgery.
Assessed left ventricular function one year post-surgery.
Focused on individuals with obesity and no prior cardiac conditions.
Marked reduction in epicardial adipose tissue observed post-surgery.
Improvement in left ventricular function noted at one-year follow-up.
Indicated that epicardial adipose tissue could serve as a marker for heart disease in obesity.

Structured PICO

Does bariatric surgery improve cardiac function and is this improvement associated with epicardial adipose tissue reduction in individuals with obesity without established cardiac disease?

Population

142 subjects aged 35-65 years with obesity (BMI ≥ 35 kg/m2) without known cardiac disease, referred for bariatric surgery. Mean age 51.6, 80% female, mean BMI 42.2 kg/m2. Conducted in The Netherlands.

Intervention

Bariatric surgery

Outcome

Improvement in cardiac function (composite of systolic function [EF or GLS], diastolic function [E/e' ratio or septal e' velocity], and cardiac remodeling [LAVI or LVMI]) and its association with epicardial adipose tissue (EAT) reduction at one yearsurrogate

Reduction in epicardial adipose tissue following bariatric surgery is independently associated with improved left ventricular function, highlighting EAT as a potential marker for early cardiac dysfunction in obesity.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

EAT reduction post-bariatric surgery was associated with LV function improvement one-year after bariatric surgery in individuals with obesity without established cardiac disease. Our results underscore the potential role of EAT as a marker of functional heart disease in obesity.

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