Why the study?
Racial and ethnic disparities have been reported with CAD and dementia/AD-related diagnoses, prompting investigation into disparities concerning coronary interventions and incident non-vascular and AD-related dementia diagnoses.
Does self-reported Black race increase the risk of incident non-vascular dementia and Alzheimer's disease-related diagnoses compared to White race among patients undergoing coronary interventions (PCI or CABG)?
Population
47,210 CAD patients who underwent PCI or CABG between 2010 and 2020
Comparison
PCI vs CABG, stratified by self-reported race
Design
Multi-site healthcare network registry-based cohort study
Follow-up
Median six years
Key result
Black patients with CABG have a 1.85-fold higher risk of non-vascular dementia compared to White patients, indicating significant racial disparities in dementia diagnoses.
Authors
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May warrant closer dementia surveillance after CABG in Black patients; leaves open mechanisms and whether disparities are modifiable.
Does self-reported Black race increase the risk of incident non-vascular dementia and Alzheimer's disease-related diagnoses compared to White race among patients undergoing coronary interventions (PCI or CABG)?
Black patients undergoing CABG have a significantly higher risk of developing non-vascular dementia and Alzheimer's disease compared to White patients, highlighting a critical racial disparity in post-revascularization cognitive outcomes.
Sayed et al. (2025) studied this question. Black patients with CABG have a 1.85-fold higher risk of non-vascular dementia compared to White patients, indicating significant racial disparities in dementia diagnoses.