What question did this study set out to answer?

This study aims to evaluate how certain risk predictors affect long-term outcomes in diabetes patients undergoing CABG.

January 10, 2026MedicinaOpen Access

Impact of Periprocedural Risk Predictors on Long-Term Outcomes in Patients with Diabetes Undergoing Coronary Artery Bypass Grafting

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Key result

Diabetes is linked to ~30% higher long-term mortality after isolated CABG.

HR 1.3
p = 0.013

Why the study?

The study aimed to analyze the impact of risk predictors on long-term outcomes in patients with diabetes undergoing isolated CABG.

Does the presence of diabetes mellitus increase the risk of long-term all-cause death and MACCE in patients undergoing isolated CABG?

Key Points

This study aims to evaluate how certain risk predictors affect long-term outcomes in diabetes patients undergoing CABG.
Included all consecutive patients undergoing isolated CABG from May 2005 to June 2021
Compared baseline demographics and pre-operative characteristics between diabetic and non-diabetic patients
Used propensity-matched analysis to examine outcomes
Primary outcome measured was long-term incidence of all-cause death
Among 4871 total patients, 1589 pairs were identified after propensity matching
Diabetic patients had a 13.5% incidence of all-cause death compared to 10.6% for non-diabetic patients (HR 1.3, p = 0.013)
MACCE occurrence was significantly higher in diabetic patients (HR 1.3, p = 0.049)
Diabetes was identified as an independent predictor for all-cause mortality (HR 1.4, CI 1.2, 1.7)

Structured PICO

Does the presence of diabetes mellitus increase the risk of long-term all-cause death and MACCE in patients undergoing isolated CABG?

Population

4,871 consecutive patients undergoing isolated coronary artery bypass grafting (CABG) between May 2005 and June 2021 (propensity-matched to 1,589 pairs of patients with and without diabetes)

Intervention

Presence of diabetes mellitus

Comparator

Absence of diabetes mellitus

Outcome

Long-term incidence of all-cause deathhard clinical

Diabetes mellitus is an independent predictor of worse long-term survival and higher MACCE rates following isolated CABG.

Discussion

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Implication

Diabetes warrants closer post-CABG surveillance in clinical practice; reinforces consensus from prior observational data.

Cite This Study

Dokollari et al. (2025) studied this question. Patients with diabetes undergoing isolated CABG had a 13.5% incidence of all-cause death versus 10.6% in non-diabetics (HR 1.3, p = 0.013), indicating poorer long-term outcomes.

synapsesocial.com/papers/6963221691e05aa366cb8921 https://doi.org/10.3390/medicina62010071

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Impact of Periprocedural Risk Predictors on Long-Term Outcomes in Patients with Diabetes Undergoing Coronary Artery Bypass Grafting

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Impact of Periprocedural Risk Predictors on Long-Term Outcomes in Patients with Diabetes Undergoing Coronary Artery Bypass Grafting

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider