What question did this study set out to answer?

The aim is to enhance the accuracy of tDCS-induced electric field simulations by using realistic head models of stroke lesions.

January 10, 2026NeuroImage Clinical0 citationsOpen Access

Simulating tDCS-induced electric fields in stroke patients: Realistic-lesion head models are needed

IKIkko KimuraAmager Hospital ŞEŞafak ErGriffith University DADaria AntonenkoUniversitätsmedizin Greifswald

Key Result

Realistic head models of stroke lesions substantially improve the accuracy of tDCS-induced electric field simulations for personalized rehabilitation protocols.

Key Points

The aim is to enhance the accuracy of tDCS-induced electric field simulations by using realistic head models of stroke lesions.
Simulated tDCS electric fields in stroke patients.
Developed head models with realistic lesion shapes and sizes.
Analyzed variability in electric fields across different montages.
Stroke lesions led to significant variability in electric field distribution.
Realistic head models improved the accuracy of electric field simulations.
Individualized tDCS protocols may enhance rehabilitation outcomes.

Structured PICO

Population

Stroke patients

Intervention

tDCS simulations using realistic-lesion head models

Outcome

tDCS-induced E-fieldssurrogate

Realistic-lesion head models are needed to improve the accuracy of individualized tDCS simulations in stroke rehabilitation.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Stroke lesions affect tDCS-induced E-fields with substantial variability across montages and individuals. These findings support the use of head models that include realistic representations of the shape, size and conductivity of the lesions to improve the accuracy of individualized tDCS simulations and guide personalized stimulation protocols in stroke rehabilitation.

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