Minimally invasive implantation of the new KONECT RESILIA aortic valved conduit: First clinical series

Jakub Staromłyński; Markus Kofler; Radosław Smoczyński; Michał Pasierski; Maciej Bartczak; Mikalay Yudo; Jakub Brączkowski; Sabina Sadecka; Kasper Buczma; Katarzyna Krzyżak; Natalia Ogorzelec; Wojciech Nowak; Dominik Drobiński; Mariusz Kowalewski; Jörg Kempfert; Wojciech Sarnowski; Piotr Suwalski

doi:10.33963/v.phj.110344

December 23, 2025Kardiologia PolskaOpen Access

Minimally invasive implantation of the new KONECT RESILIA aortic valved conduit: First clinical series

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Why the study?

Is minimally invasive implantation of the KONECT RESILIA aortic valved conduit feasible and safe in patients undergoing aortic root replacement?

Key Points

To evaluate the feasibility, safety, and early clinical outcomes of minimally invasive implantation of the KONECT RESILIA aortic valved conduit in patients requiring aortic root replacement.
Analyzed consecutive patients undergoing bio-Bentall procedures with the KONECT RESILIA conduit (N=7: 6 in Warsaw, Poland and 1 live demonstration from Berlin, Germany) enrolled in the prospective MIRAGE registry (NCT04814238).
All surgical procedures were conducted via an upper J-shaped ministernotomy utilizing central aortic cannulation, percutaneous femoral venous cannulation, and Custodiol crystalloid cardioplegia.
In-hospital and 30-day mortality was 0%, with no strokes, renal failure, re-explorations for bleeding, or permanent pacemaker implantations reported.
Postoperative echocardiography revealed satisfactory hemodynamics with a mean transvalvular gradient of 8 (1) mm Hg and no paravalvular leaks, alongside a median ICU stay of 33 hours (28–38) and hospital stay of 6 days (4–9).

Structured PICO

Is minimally invasive implantation of the KONECT RESILIA aortic valved conduit feasible and safe in patients undergoing aortic root replacement?

P

Population

7 patients eligible for a bio-Bentall procedure (aortic root replacement), mean age 60 (11) years, 86% male, with aortic root aneurysm and complex aortic valve disease.

I

Intervention

Aortic root replacement utilizing the KONECT RESILIA aortic valved conduit via an upper J-shaped ministernotomy approach.

O

Outcome

Feasibility, safety, and early clinical outcomes including in-hospital mortality, major postoperative complications, and early prosthetic valve function.safety

Minimally invasive implantation of the KONECT RESILIA aortic valved conduit for aortic root replacement is feasible and safe, demonstrating excellent early hemodynamic performance.

Limitations

Small cohort size
Absence of a comparator group
Short observation period

Implication

Supports feasibility in small series; leaves open need for larger prospective trials before wider adoption.

Abstract

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Discussion

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Cite This Study

Staromłyński et al. (2025) studied this question.

synapsesocial.com/papers/6963222f91e05aa366cb8bfd https://doi.org/10.33963/v.phj.110344

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Minimally invasive implantation of the new KONECT RESILIA aortic valved conduit: First clinical series

Key Points

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

Minimally invasive implantation of the new KONECT RESILIA aortic valved conduit: First clinical series

Key Points

Structured PICO

Limitations

Implication

Abstract

Discussion

Cite This Study

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