Key result
CMR-confirmed LVNC linked to reduced global LV longitudinal strain, driven by pronounced apical impairment.
Why the study?
Do two-dimensional speckle-tracking echocardiography and cardiac magnetic resonance imaging identify impaired longitudinal strain in adults with CMR-confirmed left ventricular non-compaction?
Do two-dimensional speckle-tracking echocardiography and cardiac magnetic resonance imaging identify impaired longitudinal strain in adults with CMR-confirmed left ventricular non-compaction?
In patients with left ventricular non-compaction, longitudinal strain is reduced globally with more pronounced apical impairment, and speckle-tracking echocardiography shows reasonable concordance with cardiac magnetic resonance in mid-apical regions.
Patients with CMR-confirmed LVNC demonstrated reduced global LS and a consistent pattern of more pronounced apical strain impairment. STE and CMR showed reasonable concordance in mid-apical regions, supporting the complementary role of deformation imaging in the evaluation of LVNC. Incorporating LS into routine assessment may improve detection of functional impairment. Further studies are needed to determine the optimal strain-based approach and clarify its relationship with underlying anatomical abnormalities.
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Sharifkazemi et al. (2025) studied this question. Patients with CMR-confirmed LVNC showed reduced global left ventricular longitudinal strain, particularly with more pronounced apical strain impairment.
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