January 10, 2026Ahi Evran Medical Journal0 citationsOpen Access

The Association Between Platelet Mass Index and Morning Blood Pressure Surge in Newly Diagnosed Hypertensive Patients

Q: What does this research mean for the field?

Higher Platelet Mass Index (PMI) is associated with significantly elevated Morning Blood Pressure Surge in newly diagnosed hypertensive patients. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

AYAlp YıldırımAhi Evran University MAMuhammet Salih AteşAhi Evran University

Key Result

Higher Platelet Mass Index (PMI) was associated with significantly elevated Morning Blood Pressure Surge in newly diagnosed hypertensive patients.

Key Points

The study aims to investigate the relationship between platelet mass index and morning blood pressure surge in newly diagnosed hypertensive patients.
Conducted a cross-sectional study with hypertensive and normotensive individuals.
Monitored blood pressure using ambulatory blood pressure monitoring (ABPM).
Calculated morning blood pressure surge (MBPS) and platelet mass index (PMI).
Assessed the predictive ability of PMI for elevated MBPS using receiver operating characteristic (ROC) curve analysis.
Hypertensive group exhibited significantly higher systolic and diastolic blood pressure compared to normotensive group.
Higher platelet count and PMI were noted in hypertensive individuals with elevated MBPS.
PMI showed predictive value for identifying elevated MBPS among hypertensive patients.

Structured PICO

Is Platelet Mass Index associated with Morning Blood Pressure Surge in newly diagnosed hypertensive patients?

Population

349 individuals (158 newly diagnosed hypertensive and 191 normotensive) evaluated at a tertiary cardiology outpatient clinic.

Intervention

Platelet Mass Index (PMI) measurement (calculated by multiplying platelet count by mean platelet volume).

Comparator

Normotensive individuals and patients with lower Morning Blood Pressure Surge (MBPS).

Outcome

Relationship between Platelet Mass Index (PMI) and Morning Blood Pressure Surge (MBPS), and the predictive ability of PMI for identifying elevated MBPS.surrogate

Elevated Platelet Mass Index is associated with a higher morning blood pressure surge in newly diagnosed hypertensive patients, suggesting a link between platelet activation and morning blood pressure dynamics.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Purpose: This study aimed to evaluate the relationship between Platelet Mass Index (PMI) and Morning Blood Pressure Surge (MBPS) in patients with newly diagnosed hypertension. Materials and Methods: A cross-sectional study was conducted between January and April 2025 at a tertiary cardiology outpatient clinic, including 158 hypertensive and 191 normotensive individuals. Blood pressure was monitored using Ambulatory Blood Pres-sure Monitoring (ABPM), and MBPS was calculated. PMI was derived by multiplying the platelet count by the mean platelet volume (MPV). The predictive ability of PMI for identifying elevated MBPS was assessed via receiver operating characteristic (ROC) curve analysis. Results: Systolic and diastolic blood pressure values across 24-hour, daytime, and nighttime measurements were significantly higher in the hypertensive group (all p28.2 mmHg showed significantly higher platelet count, PMI, PLR, and neutrophil levels (p

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